Uninterrupted monitoring of drug effects in human-induced pluripotent stem cell-derived cardiomyocytes with bioluminescence Ca2+ microscopy

<h4>Objective</h4> <p>Cardiomyocytes derived from human-induced pluripotent stem cells are a powerful platform for high-throughput drug screening in vitro. However, current modalities for drug testing, such as electrophysiology and fluorescence imaging have inherent drawbacks. To...

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Bibliographic Details
Main Authors: Suzuki, K, Onishi, T, Nakada, C, Takei, S, Daniels, M, Nakano, M, Matsuda, T, Nagai, T
Format: Journal article
Language:English
Published: BioMed Central 2018