Reduced fertilization after ICSI and abnormal phospholipase C zeta presence in spermatozoa from the wobbler mouse.

Failed fertilization after intracytoplasmic sperm injection (ICSI) can be due to a reduced oocyte-activation capacity caused by reduced concentrations and abnormal localization of the oocyte-activation factor phospholipase C (PLC) zeta. Patients with this condition can be helped to conceive by artif...

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Bibliographic Details
Main Authors: Heytens, E, Schmitt-John, T, Moser, J, Jensen, N, Soleimani, R, Young, C, Coward, K, Parrington, J, De Sutter, P
Format: Journal article
Language:English
Published: 2010