A randomised evaluation of low-dose cytosine arabinoside (ara-C) plus tosedostat versus low-dose ara-C in older patients with acute myeloid leukaemia: results of the LI-1 trial

Older patients with acute myeloid leukaemia (AML) account for nearly half of those with the disease. Because they are perceived to be unfit for, unwilling to receive, or unlikely to benefit from conventional chemotherapy they represent an important unmet need. Tosedostat is a selective oral aminopep...

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Bibliographic Details
Main Authors: Dennis, M, Burnett, A, Hills, R, Thomas, I, Ariti, C, Severinsen, MT, Hemmaway, C, Greaves, P, Clark, RE, Copland, M, Russell, N, National Cancer Research Institute (NCRI) acute myeloid leukaemia (AML) Working Group
Format: Journal article
Language:English
Published: Wiley 2021