UMI-tools: Modelling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy.
Unique Molecular Identifiers (UMIs) are random oligonucleotide barcodes that are increasingly used in high-throughput sequencing experiments. Through a UMI, identical copies arising from distinct molecules can be distinguished from those arising through PCR-amplification of the same molecule. Howeve...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
Cold Spring Harbor Laboratory Press
2017
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