UMI-tools: Modelling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy.
Unique Molecular Identifiers (UMIs) are random oligonucleotide barcodes that are increasingly used in high-throughput sequencing experiments. Through a UMI, identical copies arising from distinct molecules can be distinguished from those arising through PCR-amplification of the same molecule. Howeve...
Главные авторы: | , , |
---|---|
Формат: | Journal article |
Язык: | English |
Опубликовано: |
Cold Spring Harbor Laboratory Press
2017
|