UMI-tools: Modelling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy.

Unique Molecular Identifiers (UMIs) are random oligonucleotide barcodes that are increasingly used in high-throughput sequencing experiments. Through a UMI, identical copies arising from distinct molecules can be distinguished from those arising through PCR-amplification of the same molecule. Howeve...

Полное описание

Библиографические подробности
Главные авторы: Smith, T, Heger, A, Sudbery, I
Формат: Journal article
Язык:English
Опубликовано: Cold Spring Harbor Laboratory Press 2017