The C-terminal 79 amino acids of the herpes simplex virus regulatory protein, Vmw65, efficiently activate transcription in yeast and mammalian cells in chimeric DNA-binding proteins.

Activation of herpes simplex virus immediate early gene expression normally requires the formation of a ternary complex between a virus trans-activator, Vmw65, a cellular octamer-binding protein, TRF and the cis-acting target sequence, the TAATGARAT motif. We report that the C-terminal 79 amino acid...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Cousens, D, Greaves, R, Goding, C, O'Hare, P
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 1989