MRI reveals that early changes in cerebral blood volume precede blood-brain barrier breakdown and overt pathology in MS-like lesions in rat brain.

Magnetic resonance imaging (MRI) is an established clinical tool for diagnosing multiple sclerosis (MS), the archetypal central nervous system neuroinflammatory disease. In this study, we have used a model of delayed-type hypersensitivity in the rat brain, which bears many of the hallmarks of an MS...

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Bibliographic Details
Main Authors: Broom, K, Anthony, D, Blamire, A, Waters, S, Styles, P, Perry, V, Sibson, N
Format: Journal article
Language:English
Published: 2005