MRI reveals that early changes in cerebral blood volume precede blood-brain barrier breakdown and overt pathology in MS-like lesions in rat brain.
Magnetic resonance imaging (MRI) is an established clinical tool for diagnosing multiple sclerosis (MS), the archetypal central nervous system neuroinflammatory disease. In this study, we have used a model of delayed-type hypersensitivity in the rat brain, which bears many of the hallmarks of an MS...
Main Authors: | Broom, K, Anthony, D, Blamire, A, Waters, S, Styles, P, Perry, V, Sibson, N |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2005
|
Similar Items
-
Reactivation of immune response causes increased cerebral blood volume
by: Broom, K, et al.
Published: (2004) -
Interleukin-1beta -induced changes in blood-brain barrier permeability, apparent diffusion coefficient, and cerebral blood volume in the rat brain: a magnetic resonance study.
by: Blamire, A, et al.
Published: (2000) -
Application of MRI to the investigation or inflammatory cytokine effects in the brain
by: Sibson, N, et al.
Published: (2000) -
Endothelial edema precedes blood-brain barrier breakdown in early time points after experimental focal cerebral ischemia
by: Martin Krueger, et al.
Published: (2019-02-01) -
Blood-brain barrier breakdown in brain ischemia: Insights from MRI perfusion imaging
by: Sarvin Sasannia, et al.
Published: (2025-01-01)