MRI reveals that early changes in cerebral blood volume precede blood-brain barrier breakdown and overt pathology in MS-like lesions in rat brain.

MRI reveals that early changes in cerebral blood volume precede blood-brain barrier breakdown and overt pathology in MS-like lesions in rat brain.

Magnetic resonance imaging (MRI) is an established clinical tool for diagnosing multiple sclerosis (MS), the archetypal central nervous system neuroinflammatory disease. In this study, we have used a model of delayed-type hypersensitivity in the rat brain, which bears many of the hallmarks of an MS...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Broom, K, Anthony, D, Blamire, A, Waters, S, Styles, P, Perry, V, Sibson, N
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2005

Những quyển sách tương tự

Reactivation of immune response causes increased cerebral blood volume
Bằng: Broom, K, et al.
Được phát hành: (2004)

Interleukin-1beta -induced changes in blood-brain barrier permeability, apparent diffusion coefficient, and cerebral blood volume in the rat brain: a magnetic resonance study.
Bằng: Blamire, A, et al.
Được phát hành: (2000)

Application of MRI to the investigation or inflammatory cytokine effects in the brain
Bằng: Sibson, N, et al.
Được phát hành: (2000)

Endothelial edema precedes blood-brain barrier breakdown in early time points after experimental focal cerebral ischemia
Bằng: Martin Krueger, et al.
Được phát hành: (2019-02-01)

Blood-brain barrier breakdown in brain ischemia: Insights from MRI perfusion imaging
Bằng: Sarvin Sasannia, et al.
Được phát hành: (2025-01-01)

TNF-alpha reduces cerebral blood volume and disrupts tissue homeostasis via an endothelin- and TNFR2-dependent pathway.
Bằng: Sibson, N, et al.
Được phát hành: (2002)

MRI detection of early endothelial activation in brain inflammation.
Bằng: Sibson, N, et al.
Được phát hành: (2004)

Acute astrocyte activation in brain detected by MRI
Bằng: Sibson, N, et al.
Được phát hành: (2007)

Microbubbles containing lysolipid enhance ultrasound‐mediated blood–brain barrier breakdown in vivo
Bằng: Vince, O, et al.
Được phát hành: (2020)

Abnormal cerebral blood volume in regions of contused and normal appearing brain following traumatic brain injury using perfusion magnetic resonance imaging.
Bằng: Garnett, MR, et al.
Được phát hành: (2001)

Blood-brain barrier pathology in cerebral small vessel disease
Bằng: Ruxue Jia, et al.
Được phát hành: (2024-01-01)

Region-specific effects of a tyrosine-free amino acid mixture on amphetamine-induced changes in BOLD fMRI signal in the rat brain.
Bằng: Preece, M, et al.
Được phát hành: (2007)

The role of plasmalemma vesicle-associated protein in pathological breakdown of blood–brain and blood–retinal barriers: potential novel therapeutic target for cerebral edema and diabetic macular edema
Bằng: Esmeralda K. Bosma, et al.
Được phát hành: (2018-09-01)

Blood–brain barrier breakdown in dementia with Lewy bodies
Bằng: Jinghuan Gan, et al.
Được phát hành: (2024-09-01)

Microenvironmental Variations After Blood-Brain Barrier Breakdown in Traumatic Brain Injury
Bằng: Yue Hu, et al.
Được phát hành: (2021-11-01)

Opening of the blood-brain barrier before cerebral pathology in mild hyperhomocysteinemia.
Bằng: Bryce C Rhodehouse, et al.
Được phát hành: (2013-01-01)

Blood-brain barrier hyperpermeability precedes demyelination in the cuprizone model
Bằng: Stefan A. Berghoff, et al.
Được phát hành: (2017-12-01)

CXC chemokines generate age-related increases in neutrophil-mediated brain inflammation and blood-brain barrier breakdown.
Bằng: Anthony, D, et al.
Được phát hành: (1998)

MRI and MRS alterations in the preclinical phase of murine prion disease: association with neuropathological and behavioural changes.
Bằng: Broom, K, et al.
Được phát hành: (2007)

Loss of the tight junction proteins occludin and ZO-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo.
Bằng: Bolton, S, et al.
Được phát hành: (1998)

Acute astrocyte activation in brain detected by MRI: new insights into T(1) hypointensity.
Bằng: Sibson, N, et al.
Được phát hành: (2008)

Acute astrocyte activation in brain detected by MRI: New insights into T1 hypointensity
Bằng: Sibson, N, et al.
Được phát hành: (2008)

Reversible demyelination, blood-brain barrier breakdown, and pronounced neutrophil recruitment induced by chronic IL-1 expression in the brain.
Bằng: Ferrari, C, et al.
Được phát hành: (2004)

Reactive Inhibitory Control Precedes Overt Stuttering Events
Bằng: Joan Orpella, et al.
Được phát hành: (2024-06-01)

Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo.
Bằng: Bolton, S, et al.
Được phát hành: (1998)

A Novel Method for Assessing Cerebral Edema, Infarcted Zone and Blood-Brain Barrier Breakdown in a Single Post-stroke Rodent Brain
Bằng: Ruslan Kuts, et al.
Được phát hành: (2019-10-01)

Breakdown of blood brain barrier as a mechanism of post-traumatic epilepsy
Bằng: Aaron Dadas, et al.
Được phát hành: (2019-03-01)

Beyond blood brain barrier breakdown – <it>in vivo </it>detection of occult neuroinflammatory foci by magnetic nanoparticles in high field MRI
Bằng: Schnorr Joerg, et al.
Được phát hành: (2009-08-01)

The role of platelets in the blood-brain barrier during brain pathology
Bằng: Weifeng Lv, et al.
Được phát hành: (2024-01-01)

Expression of aquaporin 4 and breakdown of the blood-brain barrier after hypoglycemia-induced brain edema in rats.
Bằng: Jiangshan Deng, et al.
Được phát hành: (2014-01-01)

Histone methyltransferase Smyd2 contributes to blood‐brain barrier breakdown in stroke
Bằng: Jinghuan Wang, et al.
Được phát hành: (2022-03-01)

Research progress of neuroimaging of blood-brain barrier breakdown in Alzheimer's disease patients
Bằng: Qin XU, et al.
Được phát hành: (2017-06-01)

17β-estradiol attenuates breakdown of blood–brain barrier and hemorrhagic transformation induced by tissue plasminogen activator in cerebral ischemia
Bằng: Mingchang Li, et al.
Được phát hành: (2011-12-01)

Human cerebral malaria and the blood-brain barrier.
Bằng: Medana, I, et al.
Được phát hành: (2006)

Cerebral Blood Flow in Severe Brain Injuries
Bằng: A. V. Leonov
Được phát hành: (2008-04-01)

Relations between BOLD fMRI-derived resting brain activity and cerebral blood flow.
Bằng: Zhengjun Li, et al.
Được phát hành: (2012-01-01)

Evidence that increased 5-HT release evokes region-specific effects on blood-oxygenation level-dependent functional magnetic resonance imaging responses in the rat brain.
Bằng: Preece, M, et al.
Được phát hành: (2009)

Regional differences in neurovascular coupling in rat brain as determined by fMRI and electrophysiology.
Bằng: Sloan, H, et al.
Được phát hành: (2010)

Acute astrocyte activation in brain detected by MRI: new insights into T-1 hypointensity (vol 28, pg 621, 2008)
Bằng: Sibson, N, et al.
Được phát hành: (2008)

Oral fingolimod (FTY720) therapy reduces blood brain barrier breakdown, microglial activation, and leukocyte recruitment in a focal DTH model of multiple sclerosis
Bằng: Anthony, D, et al.
Được phát hành: (2009)