The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5 years of age.

The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5 years of age.

<h4>Aims/hypothesis</h4> <p>The genetic risk of type 1 diabetes has been extensively studied. However, the genetic determinants of age at diagnosis (AAD) of type 1 diabetes remain relatively unexplained. Identification of AAD genes and pathways could provide insight into the earli...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Inshaw, J, Walker, N, Wallace, C, Bottolo, L, Todd, J
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	Springer 2017

Ижил төстэй зүйлс

Evidence of linkage to chromosome 9q22.33 in colorectal cancer kindreds from the United Kingdom.
-н: Kemp, Z, зэрэг
Хэвлэсэн: (2006)

Fine-scale mapping of chromosome 9q22.33 identifies candidate causal variant in ovarian cancer
-н: Tongyu Xing, зэрэг
Хэвлэсэн: (2024-02-01)

22.033 / 22.33 Nuclear Systems Design Project, Fall 2002
-н: Kadak, Andrew
Хэвлэсэн: (2002)

Turner syndrome due to Xp22.33 deletion combined with 7p22.3 duplication
-н: Ha young Jo, зэрэг
Хэвлэсэн: (2023-02-01)

Prenatally detected six duplications at Xp22.33-p11.22: a case report
-н: Xue Zhang, зэрэг
Хэвлэсэн: (2023-04-01)

Common variants at 9q22.33, 14q13.3, and ATM loci, and risk of differentiated thyroid cancer in the French Polynesian population.
-н: Stéphane Maillard, зэрэг
Хэвлэсэн: (2015-01-01)

Prenatal diagnosis of familial 2q13 microduplication and a de novo Xp22.33 microdeletion in a pregnancy associated with an asymptomatic mother carrier
-н: Chih-Ping Chen
Хэвлэсэн: (2025-01-01)

Prenatal diagnosis of familial 46,X,del(X)(q27.1) with an Xq27.1-q28 deletion and an Xp22.33 microduplication in an asymptomatic mother carrier
-н: Chih-Ping Chen
Хэвлэсэн: (2025-03-01)

A Rare Novel Copy Number Variation of Xp22.33-p11.22 Duplication is Associated with Congenital Heart Defects
-н: Juan Zhang, зэрэг
Хэвлэсэн: (2015-01-01)

A novel Xp11.22–22.33 deletion suggesting a possible mechanism of congenital cervical spinal muscular atrophy
-н: Jingwei Liu, зэрэг
Хэвлэсэн: (2021-03-01)

Molecular cytogenetic characterization of de novo concomitant proximal 21q deletion of 21q11.2q21.3 and distal Xp deletion of Xp22.33p22.2 due to an unbalanced X;21 translocation detected by amniocentesis
-н: Chih-Ping Chen, зэрэг
Хэвлэсэн: (2023-01-01)

A foetus with 18p11.32-q21.2 duplication and Xp22.33-p11.1 deletion derived from a maternal reciprocal translocation t(X;18)(q13;q21.3)
-н: Jun-Kun Chen, зэрэг
Хэвлэсэн: (2018-06-01)

Age of diagnosis for children with chromosome 15q syndromes
-н: Anne C. Wheeler, зэрэг
Хэвлэсэн: (2023-11-01)

Molecular cytogenetic characterization of del(X)(p22.33)mat and de novo dup(4)(q34.3q35.2) in a male fetus with multiple anomalies of facial dysmorphism, ventriculomegaly, congenital heart defects, short long bones and clinodactyly
-н: Chih-Ping Chen, зэрэг
Хэвлэсэн: (2023-05-01)

Crystal Structure of Tricyclohexyltin 2,2,3,3- Tetramethylcyclopropanecarbocylate
-н: Song, Xueqing, зэрэг
Хэвлэсэн: (2004-10-01)

Genetic variants predisposing most strongly to type 1 diabetes diagnosed under age 7 years lie near candidate genes that function in the immune system and in pancreatic β-cells
-н: Inshaw, J, зэрэг
Хэвлэсэн: (2019)

MAPPING OF CHROMOSOME 22Q13.31 TO THE TELOMERE
-н: Mcdermid, H, зэрэг
Хэвлэсэн: (1994)

The development of Graves' disease and the CTLA-4 gene on chromosome 2q33.
-н: Heward, J, зэрэг
Хэвлэсэн: (1999)

Comparative analysis of a BAC contig of porcine chromosome 13q31-q32 and human chromosome 3q21-q22
-н: Van Zeveren Alex, зэрэг
Хэвлэсэн: (2005-09-01)

Triplication of several PAR1 genes and part of the Homo sapiens specific Yp11.2/Xq21.3 region of homology in a 46,X,t(X;Y)(p22.33;p11.2) male with schizophrenia.
-н: Ross, N, зэрэг
Хэвлэсэн: (2001)

Chromosome 22q11.2 deletion: world definition criteria, standards for diagnosis and monitoring
-н: M.A. Gonchar, зэрэг
Хэвлэсэн: (2018-02-01)

Mosaic chromosome 20q deletions are more frequent in the aging population
-н: Mitchell J. Machiela, зэрэг
Хэвлэсэн: (2017-02-01)

Profile of patients diagnosed with AIDS at age 60 and above in Brazil, from 1980 until June 2009, compared to those diagnosed at age 18 to 59
-н: Marise Oliveira Fonseca, зэрэг

Profile of patients diagnosed with AIDS at age 60 and above in Brazil, from 1980 until June 2009, compared to those diagnosed at age 18 to 59
-н: Marise Oliveira Fonseca, зэрэг
Хэвлэсэн: (2012-11-01)

A genome-wide search for genes affecting the age-at-diagnosis of type 1 diabetes
-н: Syreeni, A, зэрэг
Хэвлэсэн: (2019)

Chromosome 2q33genetic polymorphisms in Tunisian endemic pemphigus foliaceus
-н: Olfa Abida, зэрэг
Хэвлэсэн: (2020-11-01)

IL-13 and chromosome 5q31-q33: problems of identifying association within regions of linkage to Graves' disease.
-н: Simmonds, M, зэрэг
Хэвлэсэн: (2005)

Human Chromosome 17q11.2-q22 Contains Typhoid Fever Susceptibility Genes
-н: Nguyen, H, зэрэг
Хэвлэсэн: (2008)

Confirmation of association of chromosome 5q31-33 with United Kingdom Caucasian Graves' disease.
-н: Simmonds, M, зэрэг
Хэвлэсэн: (2010)

Chromosomal amplifications, 3q gain and deletions of 2q33-q37 are the frequent genetic changes in cervical carcinoma
-н: Terry Mary, зэрэг
Хэвлэсэн: (2004-02-01)

Identification of a cryptic unbalanced translocation Der(22)t(12;22)(q24.33;q13.33) in a large Chinese family with Phelan-McDermid syndrome by nanopore sequencing
-н: Xingwu Wu, зэрэг
Хэвлэсэн: (2025-01-01)

Colorectal cancer linkage on chromosomes 4q21, 8q13, 12q24, and 15q22.
-н: Mine S Cicek, зэрэг
Хэвлэсэн: (2012-01-01)

Somatic copy number deletion of chromosome 22q in papillary thyroid carcinoma
-н: Olivia W Lee, зэрэг
Хэвлэсэн: (2025-01-01)

FAMILIAL CASE OF CHROMOSOME 22q11.2 DELETION SYNDROME
-н: I. A. Tuzankina, зэрэг
Хэвлэсэн: (2017-01-01)

Clinical Features of Aberrations Chromosome 22q: A Pilot Study
-н: Emine Ikbal Atli, зэрэг
Хэвлэсэн: (2022-03-01)

Dopaminergic neurons in chromosome 22q11.2 deletion syndrome
-н: Haruhisa Inoue
Хэвлэсэн: (2021-01-01)

Prostate Cancer Aggressiveness Locus on Chromosome 7832-q33 Identified by Linkage and Allelic Imbalance Studies
-н: Phillippa J. Neville, зэрэг
Хэвлэсэн: (2002-01-01)

Monosomy chromosome 21 compensated by 21q22.11q22.3 duplication in a case with small size and minor anomalies
-н: Meng Su, зэрэг
Хэвлэсэн: (2018-08-01)

Prenatal diagnosis of a maternal 7.22-Mb deletion at chromosome 4q32.2q32.3 by SNP array
-н: Pingping Zhang, зэрэг
Хэвлэсэн: (2020-04-01)

Smoking related cancers and loci at chromosomes 15q25, 5p15, 6p22.1 and 6p21.33 in the Polish population.
-н: Ewa Jaworowska, зэрэг
Хэвлэсэн: (2011-01-01)