Foxn4 directly regulates tbx2b expression and atrioventricular canal formation.
Cardiac chamber formation represents an essential evolutionary milestone that allows for the heart to receive (atrium) and pump (ventricle) blood throughout a closed circulatory system. Here, we reveal a novel transcriptional pathway between foxn4 and tbx genes that facilitates this evolutionary eve...
Main Authors: | , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2008
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