Cerebral uptake of mefloquine enantiomers in fatal cerebral malaria.

PATIENTS AND METHODS: The brain disposition of the enantiomers of the antimalarial mefloquine was studied in two post-mortem human cerebral biopsies after oral administration of the racemic mixture. BACKGROUND: Mefloquine (MQ) is an effective antimalarial drug used both for prophylaxis and treatment...

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Bibliographic Details
Main Authors: Pham, Y, Nosten, F, Farinotti, R, White, N, Gimenez, F
Format: Journal article
Language:English
Published: 1999