Functionalized magnetic resonance contrast agent selectively binds to glycoprotein IIb/IIIa on activated human platelets under flow conditions and is detectable at clinically relevant field strengths.

Recent progress in molecular magnetic resonance imaging (MRI) provides the opportunity to image cells and cellular receptors using microparticles of iron oxide (MPIOs). However, imaging targets on vessel walls remains challenging owing to the quantity of contrast agents delivered to areas of interes...

Full description

Bibliographic Details
Main Authors: von Zur Muhlen, C, von Elverfeldt, D, Choudhury, R, Ender, J, Ahrens, I, Schwarz, M, Hennig, J, Bode, C, Peter, K
Format: Journal article
Language:English
Published: 2008