Structure and elevator mechanism of the mammalian sodium/proton exchanger NHE9

Na+/H+ exchangers (NHEs) are ancient membrane‐bound nanomachines that work to regulate intracellular pH, sodium levels and cell volume. NHE activities contribute to the control of the cell cycle, cell proliferation, cell migration and vesicle trafficking. NHE dysfunction has been linked to many dise...

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Bibliographic Details
Main Authors: Winkelmann, I, Matsuoka, R, Meier, PF, Shutin, D, Zhang, C, Orellana, L, Sexton, R, Landreh, M, Robinson, CV, Beckstein, O, Drew, D
Format: Journal article
Language:English
Published: EMBO Press 2020