Influence of IL-10RA and IL-22 polymorphisms on outcome of hepatitis C virus infection.

BACKGROUND: Two receptor chains, IL-10RA and IL-10RB, are known to mediate the functions of interleukin-10 (IL-10), which has been shown to be involved in the progression of persistent hepatitis C virus (HCV) infection. Little information is available on the role of host genetic variation in IL-10 r...

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Autori principali: Hennig, B, Frodsham, A, Hellier, S, Knapp, S, Yee, L, Wright, M, Zhang, L, Thomas, H, Thursz, M, Hill, A
Natura: Journal article
Lingua:English
Pubblicazione: 2007