alpha and beta Conformational preferences in fibril forming peptides characterised using NMR and CD techniques

Peptide fragments taken from residues 18-54 of short consensus repeat 3 (SCR3) from the human complement receptor CR1 have been found in aqueous solution to slowly aggregate and form fibrils. NMR studies of the monomeric form of these peptides show that they are essentially unfolded in aqueous solut...

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Bibliographic Details
Main Authors: Pertinhez, T, Sherwood, A, Fraceto, L, Bouchard, M, Pitkeathly, M, Smith, L
Format: Journal article
Language:English
Published: 2004