Influence of aerosol delivered BCG vaccination on immunological and disease parameters following SARS-CoV-2 challenge in rhesus macaques

The tuberculosis vaccine, Bacille Calmette-Guerin (BCG), also affords protection against non-tuberculous diseases attributable to heterologous immune mechanisms such as trained innate immunity, activation of non-conventional T-cells, and cross-reactive adaptive immunity. Aerosol vaccine delivery can...

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Bibliographic Details
Main Authors: White, AD, Sibley, L, Sarfas, C, Morrison, AL, Bewley, K, Churchward, C, Fotheringham, S, Gkolfinos, K, Gooch, K, Handley, A, Humphries, HE, Hunter, L, Kennard, C, Longet, S, Mabbutt, A, Moffatt, M, Rayner, E, Tipton, T, Watson, R, Hall, Y, Bodman-Smith, M, Gleeson, F, Dennis, M, Salguero, FJ, Carroll, M, McShane, H, Cookson, W, Hopkin, J, Sharpe, S
Format: Journal article
Language:English
Published: Frontiers Media 2022