HR23B is a biomarker for tumor sensitivity to HDAC inhibitor-based therapy.
Histone deacetylase (HDAC) inhibitors are emergent cancer drugs. HR23B is a candidate cancer biomarker identified in a genome-wide loss-of-function screen which influences sensitivity to HDAC inhibitors. Because HDAC inhibitors have found clinical utility in cutaneous T-cell lymphoma (CTCL), we eval...
Main Authors: | , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2010
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