Structural remodeling of the human colonic mesenchyme in inflammatory bowel disease

Intestinal mesenchymal cells play essential roles in epithelial homeostasis, matrix remodeling, immunity, and inflammation. But the extent of heterogeneity within the colonic mesenchyme in these processes remains unknown. Using unbiased single-cell profiling of over 16,500 colonic mesenchymal cells,...

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Bibliographic Details
Main Authors: Kinchen, J, Chen, H, Parikh, K, Antanaviciute, A, Jagielowicz, M, Fawkner-Corbett, D, Ashley, N, Cubitt, L, Mellado-Gomez, E, Attar, M, Sharma, E, Wills, Q, Bowden, R, Richter, F, Ahern, D, Puri, K, Henault, J, Gervais, F, Koohy, H, Simmons, A
Format: Journal article
Language:English
Published: Cell Press 2018