Bistability in apoptosis by receptor clustering.
Apoptosis is a highly regulated cell death mechanism involved in many physiological processes. A key component of extrinsically activated apoptosis is the death receptor Fas which, on binding to its cognate ligand FasL, oligomerize to form the death-inducing signaling complex. Motivated by recent ex...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2010
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