Bistability in apoptosis by receptor clustering.

Apoptosis is a highly regulated cell death mechanism involved in many physiological processes. A key component of extrinsically activated apoptosis is the death receptor Fas which, on binding to its cognate ligand FasL, oligomerize to form the death-inducing signaling complex. Motivated by recent ex...

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Bibliographic Details
Main Authors: Ho, K, Harrington, H
Format: Journal article
Language:English
Published: Public Library of Science 2010