Highly immunogenic virally vectored T-cell vaccines cannot overcome subversion of the T-cell response by HCV during chronic infection

Highly immunogenic virally vectored T-cell vaccines cannot overcome subversion of the T-cell response by HCV during chronic infection

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An effective therapeutic vaccine for the treatment of chronic hepatitis C virus (HCV) infection, as an adjunct to newly developed directly-acting antivirals (DAA), or for the prevention of reinfection would significantly reduce the global burden of disease associated with chronic HCV infection. <...

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Bibliographic Details
Main Authors: Swadling, L, Halliday, J, Kelly, C, Brown, A, Capone, S, Ansari, M, Bonsall, D, Richardson, R, Hartnell, F, Collier, J, Ammendola, V, Del Sorbo, M, Von Delft, A, Traboni, C, Hill, A, Colloca, S, Nicosia, A, Cortese, R, Klenerman, P, Folgori, A, Barnes, E
Format: Journal article
Published: MDPI 2016

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