The structure and function of HFE.
The iron overload disease hereditary haemochromatosis (HH) occurs in about 1 in 300 Caucasians; the protein mutated in this disorder is termed HFE.(1) HFE is homologous to major histocompatibility complex (MHC) class I proteins, but unlike MHC class I molecules, HFE does not present peptides to T ce...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
2000
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