The structure and function of HFE.

The iron overload disease hereditary haemochromatosis (HH) occurs in about 1 in 300 Caucasians; the protein mutated in this disorder is termed HFE.(1) HFE is homologous to major histocompatibility complex (MHC) class I proteins, but unlike MHC class I molecules, HFE does not present peptides to T ce...

Full description

Bibliographic Details
Main Authors: Drakesmith, H, Townsend, A
Format: Journal article
Language:English
Published: 2000