The structure and function of HFE.
The iron overload disease hereditary haemochromatosis (HH) occurs in about 1 in 300 Caucasians; the protein mutated in this disorder is termed HFE.(1) HFE is homologous to major histocompatibility complex (MHC) class I proteins, but unlike MHC class I molecules, HFE does not present peptides to T ce...
Prif Awduron: | , |
---|---|
Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
2000
|