An Ago2-associated capped transcriptional start site small RNA suppresses adenovirus DNA replication

Here we show that the adenovirus major late promoter produces a 31-nucleotide transcriptional start site small RNA (MLP-TSS-sRNA) that retains the 7-methylguanosine (m7G)-cap and is incorporated onto Ago2-containing RNA-induced silencing complexes (RISC) in human adenovirus-37 infected cells. RNA po...

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Bibliographic Details
Main Authors: Kamel, W, Akusjärvi, G
Format: Journal article
Language:English
Published: Cold Spring Harbor Laboratory 2017