The molecular, cellular and pathophysiological roles of iRhom pseudoproteases

iRhom proteins are catalytically inactive relatives of rhomboid intramembrane proteases. There is a rapidly growing body of evidence that these pseudoenzymes have a central function in regulating inflammatory and growth factor signalling and consequent roles in many diseases. iRhom pseudoproteases h...

Descripción completa

Detalles Bibliográficos
Autores principales: Dulloo, I, Muliyil, S, Freeman, M
Formato: Journal article
Lenguaje:English
Publicado: Royal Society 2019