The molecular, cellular and pathophysiological roles of iRhom pseudoproteases
iRhom proteins are catalytically inactive relatives of rhomboid intramembrane proteases. There is a rapidly growing body of evidence that these pseudoenzymes have a central function in regulating inflammatory and growth factor signalling and consequent roles in many diseases. iRhom pseudoproteases h...
Autores principales: | , , |
---|---|
Formato: | Journal article |
Lenguaje: | English |
Publicado: |
Royal Society
2019
|