The molecular, cellular and pathophysiological roles of iRhom pseudoproteases

iRhom proteins are catalytically inactive relatives of rhomboid intramembrane proteases. There is a rapidly growing body of evidence that these pseudoenzymes have a central function in regulating inflammatory and growth factor signalling and consequent roles in many diseases. iRhom pseudoproteases h...

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Autori principali: Dulloo, I, Muliyil, S, Freeman, M
Natura: Journal article
Lingua:English
Pubblicazione: Royal Society 2019