Synthesis of all‐carbon disubstituted bicyclo[1.1.1]pentanes by iron‐catalyzed Kumada cross‐coupling

Synthesis of all‐carbon disubstituted bicyclo[1.1.1]pentanes by iron‐catalyzed Kumada cross‐coupling

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1,3‐Disubstituted bicyclo[1.1.1]pentanes (BCPs) are important motifs in drug design as surrogates for p‐substituted arenes and alkynes. Access to all‐carbon disubstituted BCPs via cross coupling has to date been limited to use of the BCP as the organometallic component, which restricts scope due to...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Nugent, J, Shire, B, Caputo, DFJ, Pickford, HD, Nightingale, F, Houlsby, I, Mousseau, J, Anderson, EA
Format:	Journal article
Sprache:	English
Veröffentlicht:	Wiley 2020

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