Synthesis of all‐carbon disubstituted bicyclo[1.1.1]pentanes by iron‐catalyzed Kumada cross‐coupling

1,3‐Disubstituted bicyclo[1.1.1]pentanes (BCPs) are important motifs in drug design as surrogates for p‐substituted arenes and alkynes. Access to all‐carbon disubstituted BCPs via cross coupling has to date been limited to use of the BCP as the organometallic component, which restricts scope due to...

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Autors principals: Nugent, J, Shire, B, Caputo, DFJ, Pickford, HD, Nightingale, F, Houlsby, I, Mousseau, J, Anderson, EA
Format: Journal article
Idioma:English
Publicat: Wiley 2020