Coenzyme B induced coordination of coenzyme M via its thiol group to Ni(I) of F430 in active methyl-coenzyme M reductase.

Coenzyme B induced coordination of coenzyme M via its thiol group to Ni(I) of F430 in active methyl-coenzyme M reductase.

Methyl-coenzyme M reductase (MCR) catalyzes the reaction of methyl-coenzyme M (CH3-S-CoM) with coenzyme B (HS-CoB) to methane and CoM-S-S-CoB. At the active site, it contains the nickel porphinoid F430, which has to be in the Ni(I) oxidation state for the enzyme to be active. How the substrates inte...

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Bibliografiska uppgifter
Huvudupphovsmän: Finazzo, C, Harmer, J, Bauer, C, Jaun, B, Duin, E, Mahlert, F, Goenrich, M, Thauer, R, Van Doorslaer, S, Schweiger, A
Materialtyp: Journal article
Språk:English
Publicerad: 2003

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