Optimized Whole-Genome Amplification Strategy for Extremely AT-Biased Template.

Pathogen genome sequencing directly from clinical samples is quickly gaining importance in genetic and medical research studies. However, low DNA yield from blood-borne pathogens is often a limiting factor. The problem worsens in extremely base-biased genomes such as the AT-rich Plasmodium falciparu...

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Bibliographic Details
Main Authors: Oyola, S, Manske, M, Campino, S, Claessens, A, Hamilton, W, Kekre, M, Drury, E, Mead, D, Gu, Y, Miles, A, MacInnis, B, Newbold, C, Berriman, M, Kwiatkowski, D
Format: Journal article
Language:English
Published: 2014