Determination of midazolam and its major metabolite 1'-hydroxymidazolam by high-performance liquid chromatography-electrospray mass spectrometry in plasma from children.

We have developed a sensitive, selective and reproducible reversed-phase high-performance liquid chromatography method coupled with electrospray ionization mass spectrometry (HPLC-ESI-MS) for the simultaneous quantification of midazolam (MDZ) and its major metabolite, 1'-hydroxymidazolam (1...

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Príomhchruthaitheoirí: Muchohi, SN, Ward, SA, Preston, L, Newton, C, Edwards, G, Kokwaro, G
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2005