Hypoxia-induced SETX links replication stress with the unfolded protein response

Tumour hypoxia is associated with poor patient prognosis and therapy resistance. A unique transcriptional response is initiated by hypoxia which includes the rapid activation of numerous transcription factors in a background of reduced global transcription. Here, we show that the biological response...

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Bibliographic Details
Main Authors: Ramachandran, S, Ma, T, Griffin, J, Ng, N, Foskolou, I, Hwang, M-S, Victori, P, Cheng, W-C, Buffa, F, Leszczynska, K, El-Khamisy, S, Gromak, N, Hammond, E
Format: Journal article
Language:English
Published: Springer Nature 2021