Interleukin 4 induces interleukin 6 production by endothelial cells: synergy with interferon-gamma.

Interleukin (IL)4 induces IL6 production by human umbilical vein endothelial cells (HUVEC) in a dose-dependent manner, as shown by bioassay and immunoprecipitation. Interferon (IFN)-gamma, which antagonizes IL4 effects on leukocytes, synergized with IL4 in the induction of IL6 production by HUVEC. C...

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Bibliographic Details
Main Authors: Howells, G, Pham, P, Taylor, D, Foxwell, B, Feldmann, M
Format: Journal article
Language:English
Published: 1991