No evidence to support CTLA-4 as a susceptibility gene in MS families: the Canadian Collaborative Study.

Two polymorphisms of the CTLA-4 gene were genotyped in 232 sibling pairs affected with multiple sclerosis (MS) from 185 families. The CTLA-4 polymorphisms genotyped were a 3' untranslated (AT)(n) microsatellite and an alanine/threonine RFLP of exon 1. There was no evidence observed for linkage...

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Bibliographic Details
Main Authors: Dyment, D, Steckley, J, Willer, C, Armstrong, H, Sadovnick, A, Risch, N, Ebers, G
Format: Journal article
Language:English
Published: 2002