No evidence to support CTLA-4 as a susceptibility gene in MS families: the Canadian Collaborative Study.
Two polymorphisms of the CTLA-4 gene were genotyped in 232 sibling pairs affected with multiple sclerosis (MS) from 185 families. The CTLA-4 polymorphisms genotyped were a 3' untranslated (AT)(n) microsatellite and an alanine/threonine RFLP of exon 1. There was no evidence observed for linkage...
Main Authors: | , , , , , , |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
2002
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