The pharmacogenetics of NAT: structural aspects.

Arylamine N-acetyltransferases (NATs) catalyze the transfer of an acetyl group from acetyl-CoA to arylhydrazines and to arylamine drugs and carcinogens or to their N-hydroxylated metabolites. NAT plays an important role in detoxification and metabolic activation of xenobiotics and was first identifi...

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Hlavní autoři: Pompeo, F, Brooke, E, Kawamura, A, Mushtaq, A, Sim, E
Médium: Journal article
Jazyk:English
Vydáno: 2002