The pharmacogenetics of NAT: structural aspects.

Arylamine N-acetyltransferases (NATs) catalyze the transfer of an acetyl group from acetyl-CoA to arylhydrazines and to arylamine drugs and carcinogens or to their N-hydroxylated metabolites. NAT plays an important role in detoxification and metabolic activation of xenobiotics and was first identifi...

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Main Authors: Pompeo, F, Brooke, E, Kawamura, A, Mushtaq, A, Sim, E
格式: Journal article
语言:English
出版: 2002