Role of aberrant HLA-DR expression and antigen presentation in induction of endocrine autoimmunity.
Immune responses are initiated by HLA-DR+ cells, which present antigen to T cells. Observations that HLA-DR may be experimentally induced on thyroid epithelium and that HLA-DR occurs on thyrocytes in autoimmune thyroid diseases suggest a mechanism of autoimmunity with special relevance to organ-spec...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1983
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