The influence of nicotinic acid adenine dinucleotide phosphate (NAADP) signalling and the significance of the organization of lysosomes in cardiac myocytes

<p>The central role of calcium ions in the generation of contractile force in the heart has been understood for many decades. In many mammals, a large proportion of the calcium responsible for activation of the contractile apparatus is released from the sarcoplasmic reticulum (SR), and this re...