Development of advanced three-dimensional tumour models for anti-cancer drug testing

Development of advanced three-dimensional tumour models for anti-cancer drug testing

Animal testing is still the common method to test the efficacy of new drugs, but tissue engineered in vitro models are becoming more acceptable for replacing and reducing animal testing in anti-cancer drug screening by developing <em>in vitro</em> three-dimensional (3D) tumour models for...

Szczegółowa specyfikacja

Opis bibliograficzny
1. autor:	Wan, X
Kolejni autorzy:	Cui, Z
Format:	Praca dyplomowa
Język:	English
Wydane:	2014
Hasła przedmiotowe:	Medical Sciences Oncology Medical Engineering Biomedical engineering Pharmacology Cell Biology (see also Plant sciences) Vascular research Life Sciences High-Throughput Screening Tumours

Podobne zapisy

Targeting cell adhesion as a method of sensitising metastatic tumour cells to TRAIL-induced apoptosis
od: Phipps, L
Wydane: (2011)

Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte-osteoclast differentiation via induction of VEGF
od: Knowles, H, i wsp.
Wydane: (2008)

Heterogeneity of tumour response to hypoxia: carbonic anhydrase IX induction defines a subpopulation of hypoxic cells with stem cell properties and drug resistance
od: Ledaki, I
Wydane: (2013)

Reporting of prognostic studies of tumour markers: a review of published articles in relation to REMARK guidelines
od: Mallett, S, i wsp.
Wydane: (2010)

Functional analysis of cancer/testis antigens in human cancer
od: Pagotto, A
Wydane: (2013)

E2F7: a member of the E2F family with a novel mechanism of transcriptional repression
od: Kesoglidou, PX
Wydane: (2012)

Regulation of E2F-1 by methylation and NEDDylation
od: Loftus, S, i wsp.
Wydane: (2012)

The role of p53 in hypoxia-induced apoptosis
od: Poole, R
Wydane: (2010)

QuantiSNP: an Objective Bayes Hidden-Markov Model to detect and accurately map copy number variation using SNP genotyping data
od: Colella, S, i wsp.
Wydane: (2007)

Electrostatic and functional analysis of the seven-bladed WD beta-propellers
od: Valeyev, N, i wsp.
Wydane: (2008)

Disease model distortion in association studies
od: Vukcevic, D, i wsp.
Wydane: (2011)

A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
od: Howie, B, i wsp.
Wydane: (2009)

A robust clustering algorithm for identifying problematic samples in genome-wide association studies
od: Bellenguez, C, i wsp.
Wydane: (2012)

Studies on HIF hydroxylases
od: Webb, J
Wydane: (2008)

Cellular models for characterisation of MINA53, a 2-oxoglutarate-dependent dioxygenase
od: Zayer, A
Wydane: (2012)

Tumour-stroma interaction in pancreatic cancer
od: Lunardi, S
Wydane: (2013)

Trials in primary care: statistical issues in the design, conduct and evaluation of complex interventions
od: Lancaster, G, i wsp.
Wydane: (2010)

Targeting polymer coated adenovirus to tumour-associated vasculature
od: Bachtarzi, H
Wydane: (2010)

The influence of BRCA1's ubiquitin ligase activity on cell motility
od: Sengupta, S
Wydane: (2014)

Assessing the role of ADAM10 in Trastuzumab treatment and resistance
od: Feldinger, K
Wydane: (2012)

Mucosal associated invariant T cells and related CD161 expressing T lymphocytes
od: Fergusson, J, i wsp.
Wydane: (2015)

Structure-function studies of fibronectin domains in the human endometrium
od: Mok, M, i wsp.
Wydane: (2008)

Reweighting methods in high dimensional regression
od: Fang, Z
Wydane: (2012)

The role of Topoisomerase II in replication in mammalian cells
od: Muftic, D
Wydane: (2011)

HR23B, a biomarker for HDAC inhibitors
od: Khan, OA
Wydane: (2013)

Some aspects of complex statistical dependencies
od: Kartsonaki, C
Wydane: (2014)

Synonymous codon usage influences the local protein structure observed
od: Saunders, R, i wsp.
Wydane: (2010)

Markov fields and log-linear interaction models for contingency tables
od: Darroch, J, i wsp.
Wydane: (1980)

Models and software for improving the profitability of pharmaceutical research
od: Qu, S
Wydane: (2011)

Hyper Markov laws in the statistical analysis of decomposable graphical models
od: Dawid, A, i wsp.
Wydane: (1993)

Graphical models for associations between variables, some of which are quantitative and some qualitative
od: Lauritzen, S, i wsp.
Wydane: (1989)

Graphical models for genetic analyses
od: Lauritzen, S, i wsp.
Wydane: (2003)

Some problems in the theory & application of graphical models
od: Roddam, A
Wydane: (1999)

A coalescent dual process in a Moran model with genic selection, and the lambda coalescent limit
od: Etheridge, A, i wsp.
Wydane: (2010)

How threshold behaviour affects the use of subgraphs for network comparison
od: Rito, T, i wsp.
Wydane: (2010)

An approximate sampling formula under genetic hitchhiking
od: Etheridge, A, i wsp.
Wydane: (2006)

A Bayesian cost-benefit approach to sample size determination and evaluation in clinical trials
od: Kikuchi, T
Wydane: (2011)

Human orthologues of Saccharomyces cerevisiae Trf4/5 non-canonical poly(A) polymerases
od: Gibson, K
Wydane: (2011)

Course of distress in breast cancer patients, their partners, and matched control couples
od: Hinnen, C, i wsp.
Wydane: (2008)

Pathways for glycoprotein degradation in mammalian cells
od: Kukushkin, N, i wsp.
Wydane: (2011)