Stereoselective synthesis of alicyclic ketones: a hydrogen borrowing approach

A highly diastereoselective annulation strategy for the synthesis of alicyclic ketones from diols and pentamethylacetophenone is described. This process is mediated by a commercially available iridium(III) catalyst, and provides efficient access to a wide range of cyclopentane and cyclohexane produc...

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Bibliographic Details
Main Authors: Armstrong, RJ, Akhtar, WM, Frost, JR, Christensen, KE, Stevenson, NG, Donohoe, TJ
Format: Journal article
Language:English
Published: Elsevier 2019