Stereoselective synthesis of alicyclic ketones: a hydrogen borrowing approach
A highly diastereoselective annulation strategy for the synthesis of alicyclic ketones from diols and pentamethylacetophenone is described. This process is mediated by a commercially available iridium(III) catalyst, and provides efficient access to a wide range of cyclopentane and cyclohexane produc...
Main Authors: | Armstrong, RJ, Akhtar, WM, Frost, JR, Christensen, KE, Stevenson, NG, Donohoe, TJ |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2019
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