Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program

Differentiation of lineage-committed cells from multipotent progenitors requires the establishment of accessible chromatin at lineage-specific transcriptional enhancers and promoters, which is mediated by pioneer transcription factors that recruit activating chromatin remodeling complexes. Here we s...

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Bibliographic Details
Main Authors: Loughran, S, Comoglio, F, Hamey, F, Giustacchini, A, Errami, Y, Earp, E, Göttgens, B, Jacobsen, S, Mead, A, Hendrich, B, Green, A
Format: Journal article
Language:English
Published: Rockefeller University Press 2017