Fidaxomicin versus vancomycin for Clostridium difficile infection: meta-analysis of pivotal randomized controlled trials.

Two recently completed phase 3 trials (003 and 004) showed fidaxomicin to be noninferior to vancomycin for curing Clostridium difficile infection (CDI) and superior for reducing CDI recurrences. In both studies, adults with active CDI were randomized to receive blinded fidaxomicin 200 mg twice daily...

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Bibliographic Details
Main Authors: Crook, D, Walker, A, Kean, Y, Weiss, K, Cornely, O, Miller, M, Esposito, R, Louie, T, Stoesser, N, Young, B, Angus, B, Gorbach, S, Peto, T
Format: Journal article
Language:English
Published: 2012