Functional in vivo MHC class II loading by endogenously synthesized glycoprotein during viral infection.

MHC class II presentation of antigenic peptides derived from soluble proteins is usually preceded by antigenic uptake via (nonreceptor-mediated) endocytosis by professional APCs, followed by processing in endosomal compartments. Although in vitro alternative pathways for MHC class II loading have be...

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Bibliographic Details
Main Authors: Oxenius, A, Bachmann, M, Mathis, D, Benoist, C, Zinkernagel, R, Hengartner, H
Format: Journal article
Language:English
Published: 1997