Inclusion of the woodchuck hepatitis virus posttranscriptional regulatory element enhances AAV2-driven transduction of mouse and human retina
The woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) has been included in the transgene cassette of adeno-associated virus (AAV) in several gene therapy clinical trials, including those for inherited retinal diseases. However, the extent to which WPRE increases transgene expre...
| Päätekijät: | , , , , |
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| Aineistotyyppi: | Journal article |
| Julkaistu: |
American Society of Gene and Cell Therapy
2017
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