The role of nitric oxide and reactive oxygen species in the positive inotropic response to mechanical stretch in the mammalian myocardium.

The endothelial nitric oxide synthase (eNOS) has been implicated in the rapid (Frank-Starling) and slow (Anrep) cardiac response to stretch. Our work and that of others have demonstrated that a neuronal nitric oxide synthase (nNOS) localized to the myocardium plays an important role in the regulatio...

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Bibliographic Details
Main Authors: Zhang, Y, Dingle, L, Hall, R, Casadei, B
Format: Journal article
Language:English
Published: 2009