The stability of triplex DNA is affected by the stability of the underlying duplex.

We have studied the formation of DNA triple helices in different sequence contexts and show that, for the most stable triplexes, their apparent stability is affected by the stability of the underlying duplex. For a 14-mer parallel triplex-forming oligonucleotide (generating C(+).GC and T.AT triplets...

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Bibliographic Details
Main Authors: Rusling, D, Rachwal, P, Brown, T, Fox, K
Format: Journal article
Language:English
Published: 2009