The stability of triplex DNA is affected by the stability of the underlying duplex.

We have studied the formation of DNA triple helices in different sequence contexts and show that, for the most stable triplexes, their apparent stability is affected by the stability of the underlying duplex. For a 14-mer parallel triplex-forming oligonucleotide (generating C(+).GC and T.AT triplets...

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Detalhes bibliográficos
Main Authors: Rusling, D, Rachwal, P, Brown, T, Fox, K
Formato: Journal article
Idioma:English
Publicado em: 2009

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