RAD51 paralogs: roles in DNA damage signalling, recombinational repair and tumorigenesis.

Chromosomal double-strand breaks (DSBs) have the potential to permanently arrest cell cycle progression and endanger cell survival. They must therefore be efficiently repaired to preserve genome integrity and functionality. Homologous recombination (HR) provides an important error-free mechanism for...

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Bibliographic Details
Main Authors: Suwaki, N, Klare, K, Tarsounas, M
Format: Journal article
Language:English
Published: 2011